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HIV DART 2010
Frontiers in Drug Development for
Antiretroviral Therapies Click here to view the complete abstract book
Selected Slide Presentations Click on the links below to view presentations.
Reservoirs, Persistence and Eradication
Gertrude Elion Distinguished Lecturer Award Lecture:
Persistence, Resistance, Diversity: Insights into the HIV-host Interaction
John Coffin; Tufts University, USA
Prospects for HIV Eradication
Sharon Lewin; Alfred Hospital, Australia
Immunotherapies
The PD-1 Inhibitory Co-signaling Pathway in HIV Infection and the Potential for Therapeutic Intervention
Daniel Kaufmann; Harvard University, USA
Lentiviral Vectors as HIV Vaccine Candidates: A Highly Immunogenic Lentiviral Vaccine Provides Control of Viral Load, Preservation of the CD4 Compartment, and Survival Advantage Post-SIV Challenge
Franck Lemiale; VIRxSYS Corporation, USA
Viral Hepatitis Co-infection and Other HIV Co-morbidities
State of the Art Lecture:
Liver Disease and Therapy of Hepatitis B Virus Infection in HIV Infected Persons
William Mason; Fox Chase Cancer Center, USA
Co-infection with Hepatitis B
Marion Peters; University of California, San Francisco, USA
Malignancies in HIV: A Growing Problem
Ronald Mitsuyasu; University of California, Los Angeles, USA
Antiretroviral Targets
David Barry DART Achievement Award Lecture:
Pharmacokinetic Boosting: A Paradigm Shift in Antiviral Therapy
Dale Kempf; Abbott Laboratories, USA
Discovery of Novel Inhibitors of HIV-1 Reverse Transcriptase by Crystallographic Fragment Screening
Eddy Arnold; Rutgers University, USA
Small Molecule Inhibition of Human Immunodeficiency Virus Type 1 Infection by Virus Capsid Destabilization
Christopher Aiken; Vanderbilt University, USA
Treatment Strategies in Developing Countries
Infant HAART in Resource Limited Countries
Annelies Van Rie; University of North Carolina Chapel Hill, USA
Differences between HIV Subtypes in Development of Drug Resistance: The Clustering of Transmitted Resistance
Mark Wainberg; McGill AIDS Center, Canada
The Impact of CMV-associated Inflammation on HIV Disease Outcomes
Steven Deeks; University of California, San Francisco, USA
Inflammation, Pharmacology, Toxicology and Drug Metabolism
State of the Art Lecture:
Lipodystrophy and Metabolic Toxicity of Antiretroviral Therapy
David Cooper; University of New South Wales National Centre in HIV Epidemiology & Clinical Research, Australia
Chronic Inflammation and Medical Complications in HIV
David Shepp; Hofstra University School of Medicine, North Shore University Hospital, USA
HIV, Inflammation, and Cardiovascular Disease
Laurence Sperling; Emory University School of Medicine, USA
Preventing Transmission: Microbicides and Other Approaches
State of the Art Lecture: Treatment as Prevention:
Five Year Experience in British Columbia, Canada
Julio Montaner; BC Centre for Excellence in HIV/AIDS, Canada
A Pill a Day to Keep HIV Away
Robert Grant; Gladstone/UCSF, USA
Sex is Messy
Davey Smith; University of California, San Diego, USA
Novel Monitoring and Diagnostic Approaches
Predicting HIV Response to Antiretroviral Therapy
Daniel Kuritzkes; Brigham and Women?s Hospital, USA
Special Lecture:
Emerging Retroviruses: XMRV: The Link to Prostate Cancer and Chronic Fatigue Syndrome
Ila Singh; University of Utah, USA
Oral Abstract Presentations
DermaVir Therapeutic HIV Vaccine: Phase I and II Clinical Data in ARV Treated and Naïve HIV+ Subjects
Julianna Lisziewicz; Genetic Immunity, Hungary
The Preclinical and Clinical Chemokine Receptor 2 (CCR2) Activity of TBR 652, a Potent Dual CCR5/CCR2 Antagonist in Phase 2 Development for Treatment of HIV Infection
Richard Ogden; Tobira Therapeutics, Inc., USA
Development of a Cellular Immunotherapy for ART Naïve Patients for the Purpose of Delaying or Preventing Initiation of ART
Charles Nicolette; Argos Therapeutics, Inc., USA
AIC246, a Potent Novel, Well Tolerated Non-Nucleosidic Compound Against Human Cytomegalovirus (HCMV) with Resistance Breaking Potential
Helga Rübsamen-Schaeff; AiCuris, Germany
Homing Endonucleases for the Targeted Disruption of Integrated HIV
Keith Jerome; Fred Hutchinson Cancer Research Center, and University of Washington, USA
12 Week Analysis of the SENSE Trial: Etravirine versus Efavirenz in Treatment-naïve Patients
Mark Nelson; Chelsea and Westminster Hospital, UK
CMX157 (Hexadecyloxypropyl Tenofovir), a Clinical Stage Antiretroviral with Activity against HIV and XMRV
Randall Lanier; Chimerix Inc., USA
Anti-HIV Effect In Vitro of Human Milk Glycosaminoglycans
Monica Viveros-Rogel; Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico
Pooled Week 48 Efficacy and Safety Results from ECHO and THRIVE, Two Double-blind, Randomized, Phase III Trials Comparing TMC278 versus Efavirenz in Treatment-naïve, HIV-1-infected Patients
Katia Boven; Tibotec Inc., USA
HIV DART 2010 Satellite Mini-symposium: Brighter Future of HIV Therapeutics
December 7, 2010
Welcome and Overview Talk: New Drugs for HIV and Combinations
Robert Murphy; Northwestern University, USA
Integrase Inhibitors: Past, Present and Future
Daria Hazuda; Merck Research Laboratories, USA
The Clinical Implications of HIV Persistence during Therapy
Tom North; Emory University, USA
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